HIV-1 host interactions: integration of large-scale datasets
نویسنده
چکیده
HIV-1 replication and viral pathogenesis are dependent on numerous host factors. A series of recent papers apply genome-wide and large-scale approaches to map host-virus interactions and to identify host proteins capable of restricting (that is, controlling) the virus. Strategies include genome-wide association studies, small interfering RNA screens, genome-wide transcriptome profiling, proteome studies, and the assessment of the role of host-encoded microRNAs in infection. The various layers of large-scale data are brought together through meta-analytical procedures.
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عنوان ژورنال:
دوره 1 شماره
صفحات -
تاریخ انتشار 2009